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Eine verringerte Aktivität des Enzyms Methylen-Tetrahydrofolat-Reduktase (MTHFR), das an der Umwandlung von Homocystein zu Methionin beteiligt ist, kann Ursache eines erhöhten Homocysteinspiegels sein. Ein erhöhter Homocysteinspiegel im Serum wird als ein Risikofaktor für das Auftreten von atherosklerotischen Gefäßveränderungen und
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